The COVID-19 pandemic response included unprecedented infrastructure investments to support the creation, scaling and adapting of several research platforms. An important component of building an emergency-ready health research ecosystem in Canada is to ensure that key research infrastructure critical for informing decision-making during pandemics and other health emergencies is maintained between emergencies so that it can be rapidly activated when needed. To that end, and in alignment with the CRPPHE Interim investment plan, this funding opportunity aims to support existing research platforms that address all four objectives in any one of the priority research areas (listed below) that persist in Canada related to responding to pandemics and other acute public health threats of an infectious or communicable nature.